Funding Projects

Development of Polymer Optical Fibre Gratings for Endoscopic Biosensing Purpose

Titled FBG to detect chemical species

Plasmonic resonance

01/12/2011-31/11/2016 - 1 partners
  • Funding agency: Europe (ERC starting grant)

  • Coordinator(s): UMONS (Mons, Belgium)

  • Department Contribution:

  • Administrative responsible(s): C. Caucheteur; P. Mégret; M. Mura;

  • Scientific responsible(s): C. Caucheteur;

  • Related UMONS Cluster(s): Cluster Material;

  • Summary of the project: PROSPER will address this objective through the demonstration of biosensors based on a functionalized polymer optical fibre (POF) in which specially-designed refractive-index gratings have been written. Immobilised biomolecular receptors on the grafted fibre surface will allow label-free recognition through the monitoring of wavelength shifts in the grating spectral response. Such biosensors are predicted to exhibit a surrounding refractive index detection limit of 10-6 in real time, which is classical for biodetection. Although generic and able to work in various areas such as environmental monitoring, food analysis, agriculture or security, the proposed biosensors will be targeted for non-invasive medical diagnostics where they present the most ground-breaking nature. Indeed, unlike bulk structures, they require reduced reaction volumes for ex vivo measurements and present the advantageous possibility of assaying several parameters simultaneously (e.g. several cancer-associated antigens in one sample). As a result, statistical analysis of these parameters can potentially increase the reliability and reduce the measurement uncertainty of a diagnosis over single-parameter assays. More importantly, the proposed biosensors have the unique potential to be used in vivo in an endoscope (for this reason POFs are privileged over silica), which would considerably improve the diagnosis.

  • More information: see

  • 5 relevant Publications
    • V. Malachovska, C. Ribaut, V. Voisin, M. Surin, P. Leclère, R. Wattiez, C. Caucheteur,
      'Fiber-optic SPR immunosensors tailored to target epithelial cells through membrane receptors',
      Analytical Chemistry, vol. 87, n. 12, pp. 5957-5965, 2015 (2015/06/01).

    • C. Caucheteur, V. Voisin, J. Albert,
      'Near-infrared grating-assisted SPR optical fiber sensors: design rules for ultimate refractometric sensitivity',
      Optics Express, vol. 23, n. 3, pp. 2918-2932, 2015 (2015/01/30).

    • C. Caucheteur, T. Guo, J. Albert,
      'Review of plasmonic fiber optic biochemical sensors: improving the limit of detection',
      Analytical and Bioanalytical Chemistry, n. 14, 2015 (2015/01/01).

    • K. Chah, V. Voisin, D. Kinet, C. Caucheteur,
      'Surface plasmon resonance in eccentric femtosecond-laser-induced fiber Bragg gratings',
      Optics Letters, vol. 39, n. 24, pp. 6887-6890, 2014 (2014/12/08).

    • C. Caucheteur, V. Voisin, P. Mégret,
      'Light polarization-assisted sensing with tilted fiber Bragg gratings',
      The Open Optics Journal, vol. 7, pp. 95-103, 2013 (2013/12/27).

  • Show all publications related to this project: Click here